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Iminyl Radical-Triggered Intermolecular Distal C(sp 3 )-H Heteroarylation via 1,5-Hydrogen-Atom Transfer (HAT) Cascade.
- Source :
-
Organic letters [Org Lett] 2019 Feb 15; Vol. 21 (4), pp. 917-920. Date of Electronic Publication: 2019 Jan 28. - Publication Year :
- 2019
-
Abstract
- An efficient iron-catalyzed intermolecular remote C(sp <superscript>3</superscript> )-H heteroarylation of alkyl ketones has been developed via an iminyl radical-triggered 1,5-hydrogen-atom transfer (HAT) cascade. This protocol was amenable to a wide variety of alkyl ketones and heteroaryls, thus providing a straightforward method for the late-stage functionalization of alkylketones and heteroaryls.
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 21
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 30688076
- Full Text :
- https://doi.org/10.1021/acs.orglett.8b03865