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The OMERACT MRI in Enthesitis Initiative: Definitions of Key Pathologies, Suggested MRI Sequences, and a Novel Heel Enthesitis Scoring System.

Authors :
Mathew AJ
Krabbe S
Eshed I
Gandjbakhch F
Bird P
Pedersen SJ
Stoenoiu MS
Foltz V
Glinatsi D
Lambert RG
Hermann KGA
Maksymowych WP
Haugen IK
Jaremko JL
Poggenborg RP
Paschke J
Laredo JD
Carron P
Conaghan PG
Østergaard M
Source :
The Journal of rheumatology [J Rheumatol] 2019 Sep; Vol. 46 (9), pp. 1232-1238. Date of Electronic Publication: 2019 Feb 01.
Publication Year :
2019

Abstract

Objective: To develop and validate an enthesitis magnetic resonance imaging (MRI) scoring system for spondyloarthritis/psoriatic arthritis, using the heel as model.<br />Methods: Consensus definitions of key pathologies and 3 heel enthesitis multireader scoring exercises were done, separated by discussion, training, and calibration.<br />Results: Definitions for bone and soft tissue pathologies were agreed. In the final exercise, median pairwise single-measures intraclass correlation coefficients (ICC; patient-level) for entheseal inflammation status/change scores were 0.83/0.82 for all readers. For radiologists and selected rheumatologists, ICC were 0.91/0.84 and quadratic-weighted κ (lesion-level) 0.57-0.91/0.45-0.81.<br />Conclusion: The proposed definitions and Heel Enthesitis Scoring System (HEMRIS) are reliable among trained readers and promising for clinical trials.

Details

Language :
English
ISSN :
0315-162X
Volume :
46
Issue :
9
Database :
MEDLINE
Journal :
The Journal of rheumatology
Publication Type :
Academic Journal
Accession number :
30709961
Full Text :
https://doi.org/10.3899/jrheum.181093