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[Mass spectrometry virulence marker Vibrio cholerae.]

Authors :
Chaika SO
Telesmanich NR
Lomov YM
Source :
Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 2018; Vol. 63 (7), pp. 445-449.
Publication Year :
2018

Abstract

Identification mass-spectrometry of marker proteins of toxicity of V. cholerae for development the express of diagnostics of the causative agent of cholera on the basis of the computer analysis in the MALDI-ToF format of electronic profiles became the purpose of our research. Subjected to the computer analysis mass and spectrometer electronic passports 140 of strains of V. cholerae with obviously known characteristic of strains which were divided into 2 basic groups in the parameter of existence or lack of a gene of cholera toxin (ctx-and ctx+). We for the first time revealed a taxon - the specific marker protein ceous peak having a molecular mass of 3202 Da characteristic of strains of V.cholerae ctx + and unrepresentative for V.cholerae ctx-.<br />Competing Interests: The authors declare no conflict of interest.

Details

Language :
Russian
ISSN :
0869-2084
Volume :
63
Issue :
7
Database :
MEDLINE
Journal :
Klinicheskaia laboratornaia diagnostika
Publication Type :
Academic Journal
Accession number :
30720962
Full Text :
https://doi.org/10.18821/0869-2084-2018-63-7-445-449