Role of Biomechanical Factors in Resolution of Carpal Tunnel Syndrome Among a Population of Workers.

Objectives: Identify if Carpal tunnel syndrome (CTS) symptoms vary by measured biomechanical exposures.
Methods: A nested prospective cohort within a large, multicenter, 8-year cohort study. The CTS case definition was tingling/numbness in 2+ median nerve-served digits plus a nerve conduction study consistent with CTS. Workers were assigned to: (1) low (strain index [SI] less than or equal to 6.1), and (2) high (SI more than 6.1) job groups.
Results: Among 1201 workers, 106 had CTS. Those in the high SI group became and remained symptom-free for at least 3 months, faster than the low SI group, adjusted hazard ratio (HR) = 2.07 (95% confidence interval [CI] = 1.21 to 3.56, P = 0.008). Only surgical release trended towards resolving CTS. Light duty had no impact, and job change was associated with delayed symptoms resolution.
Conclusions: High biomechanical exposures paradoxically predicted faster improvement in CTS and light duty did not result in symptom resolution.