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Catheter based treatments for fibrosing mediastinitis.
- Source :
-
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions [Catheter Cardiovasc Interv] 2019 Nov 15; Vol. 94 (6), pp. 878-885. Date of Electronic Publication: 2019 Feb 21. - Publication Year :
- 2019
-
Abstract
- Fibrosing mediastinitis is a rare, often debilitating and potentially lethal disease characterized by an exuberant fibroinflammatory response within the mediastinum. Patients typically present with insidious symptoms related to compression of adjacent structures including the esophagus, heart, airways, and cardiac vessels. Fibrosing mediastinitis is most often triggered by Histoplasmosis infection; however, antifungal and anti-inflammatory therapies are largely ineffective. While structural interventions aimed at alleviating obstruction can provide significant palliation, surgical interventions are challenging with high mortality and clinical experience with percutaneous interventions is limited. Here, we will review the presentation, natural history, and treatment of fibrosing mediastinitis, placing particular emphasis on catheter-based therapies.<br /> (© 2019 Wiley Periodicals, Inc.)
- Subjects :
- Adolescent
Adult
Aged
Airway Obstruction diagnostic imaging
Airway Obstruction microbiology
Airway Obstruction mortality
Child
Female
Histoplasmosis diagnostic imaging
Histoplasmosis microbiology
Histoplasmosis mortality
Humans
Male
Mediastinitis diagnostic imaging
Mediastinitis microbiology
Mediastinitis mortality
Middle Aged
Pulmonary Veno-Occlusive Disease diagnostic imaging
Pulmonary Veno-Occlusive Disease mortality
Risk Factors
Sclerosis diagnostic imaging
Sclerosis microbiology
Sclerosis mortality
Stenosis, Pulmonary Artery diagnostic imaging
Stenosis, Pulmonary Artery mortality
Stents
Treatment Outcome
Young Adult
Airway Obstruction therapy
Bronchoscopy adverse effects
Bronchoscopy instrumentation
Bronchoscopy mortality
Endovascular Procedures adverse effects
Endovascular Procedures instrumentation
Endovascular Procedures mortality
Histoplasmosis therapy
Mediastinitis therapy
Pulmonary Veno-Occlusive Disease therapy
Sclerosis therapy
Stenosis, Pulmonary Artery therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1522-726X
- Volume :
- 94
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
- Publication Type :
- Academic Journal
- Accession number :
- 30790443
- Full Text :
- https://doi.org/10.1002/ccd.28152