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Unraveling the Paradox of Statins with Human Neurons: New Leads in Alzheimer's Disease.
- Source :
-
Cell stem cell [Cell Stem Cell] 2019 Mar 07; Vol. 24 (3), pp. 347-349. - Publication Year :
- 2019
-
Abstract
- Conflicting clinical studies have reported that statins both reduce and accelerate cognitive impairments in Alzheimer's disease. In this issue, Van der Kant et al. (2019) use iPSC-derived neurons to thoroughly dissect the link between cholesterol synthesis, phospho-Tau, and amyloid-β, revealing new therapeutic opportunities in Alzheimer's disease and related dementias.<br /> (Copyright © 2019 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1875-9777
- Volume :
- 24
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Cell stem cell
- Publication Type :
- Academic Journal
- Accession number :
- 30849361
- Full Text :
- https://doi.org/10.1016/j.stem.2019.02.003