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Survival after lobectomy versus sub-lobar resection in elderly with stage I NSCLC: a meta-analysis.
- Source :
-
BMC surgery [BMC Surg] 2019 Apr 15; Vol. 19 (1), pp. 38. Date of Electronic Publication: 2019 Apr 15. - Publication Year :
- 2019
-
Abstract
- Background: We present a critical comparison of lobectomy and sub-lobar resection in elderly patients with early stage non-small cell lung cancer using meta-analytical techniques.<br />Methods: A literature search was conducted between the period of December 1997 to March 2019 to identify the comparative studies evaluating 1-, 3-, and 5-year survival rates. The pooled odds ratios (OR) and the 95% confidence intervals (95% CI) were calculated with either the fixed or random effect models, respectively.<br />Results: Six retrospective studies are included in our meta-analysis for a total of 1205 patients. 843 of the individuals were treated with lobectomy, while 362 were treated with sub-lobar resection. We found no significant difference between the lobectomy and the sub-lobar resection in either of the 1-, 3-, or 5-year survival rates.<br />Conclusions: This study suggests that in elderly individuals with stage I NSCLC, a sub-lobar resection is statistically equivalent to the lobectomy in terms of 1-, 3-, and 5-year survival rates. Further large-scale randomized studies are needed to confirm our results.
Details
- Language :
- English
- ISSN :
- 1471-2482
- Volume :
- 19
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- BMC surgery
- Publication Type :
- Academic Journal
- Accession number :
- 30987622
- Full Text :
- https://doi.org/10.1186/s12893-019-0500-1