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Accelerated 3D T 2 w-imaging of the prostate with 1-millimeter isotropic resolution in less than 3 minutes.
- Source :
-
Magnetic resonance in medicine [Magn Reson Med] 2019 Aug; Vol. 82 (2), pp. 721-731. Date of Electronic Publication: 2019 Apr 21. - Publication Year :
- 2019
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Abstract
- Purpose: To achieve 3D T <subscript>2</subscript> w imaging of the prostate with 1-mm isotropic resolution in less than 3 min.<br />Methods: We devised and implemented a 3D T <subscript>2</subscript> -prepared multishot balanced steady state free precession (T <subscript>2</subscript> prep-bSSFP) acquisition sequence with a variable density undersampled trajectory combined with a total variation regularized iterative SENSE (TV-SENSE) reconstruction. Prospectively undersampled images of the prostate (acceleration factor R = 3) were acquired in 11 healthy subjects in an institutional review board-approved study. Image quality metrics (subjective signal-to-noise ratio, contrast, sharpness, and overall prostate image quality) were evaluated by 2 radiologists. Scores of the proposed accelerated sequence were compared using the Wilcoxon signed-rank and Kruskal-Wallis non-parametric tests to prostate images acquired using a fully sampled 3D T <subscript>2</subscript> prep-bSSFP acquisition, and with clinical standard 2D and 3D turbo spin echo (TSE) T <subscript>2</subscript> w acquisitions. A P-value < 0.05 was considered significant.<br />Results: The 3× accelerated 3D T <subscript>2</subscript> prep-bSSFP images required a scan time (min:s) of 2:45, while the fully sampled 3D T <subscript>2</subscript> prep-bSSFP and clinical standard 3D TSE images were acquired in 8:23 and 7:29, respectively. Image quality scores (contrast, sharpness, and overall prostate image quality) of the accelerated 3D T <subscript>2</subscript> prep-bSSFP, fully sampled T <subscript>2</subscript> prep-bSSFP, and clinical standard 3D TSE acquisitions along all 3 spatial dimensions were not significantly different (P > 0.05).<br />Conclusion: 3D T <subscript>2</subscript> w images of the prostate with 1-mm isotropic resolution can be acquired in less than 3 min, with image quality that is comparable to a clinical standard 3D TSE sequence but only takes a third of the acquisition time.<br /> (© 2019 International Society for Magnetic Resonance in Medicine.)
Details
- Language :
- English
- ISSN :
- 1522-2594
- Volume :
- 82
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Magnetic resonance in medicine
- Publication Type :
- Academic Journal
- Accession number :
- 31006906
- Full Text :
- https://doi.org/10.1002/mrm.27764