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Scrotal elephantiasis associated with follicular occlusion triad: A case report and literature review.
- Source :
-
Medicine [Medicine (Baltimore)] 2019 Apr; Vol. 98 (16), pp. e15263. - Publication Year :
- 2019
-
Abstract
- Rationale: Follicular occlusion triad (FOT) is an autosomal recessive inherited disease and no more than 3 variants of the triad have been reported. We give a report in which scrotal elephantiasis is a variant of FOT and further perform a literature review.<br />Patient Concerns: A 41-year-old man came to us because of a large scrotal cyst and generalized skin lesions that had occurred over the past 10 years. The generalized skin lesions consisted of hidradenitis suppurativa on the perineum and back, acne conglobata in the armpit, and dissecting cellulitis of the scalp. He took antibiotics for a long time but achieved poor effect. Furthermore, he told his father and elder brother also manifested such skin lesions.<br />Diagnoses: Magnetic resonance showed a mass in the left scrotum with clear boundaries. A routine blood test showed a high leukocyte level of 12 × 10/L and a hemoglobin content of 78 g/L. C-reactive-protein increased. Series of autoimmune antibody tests were negative. The postoperative pathologic findings showed that the mass was an epidermoid cyst, and hematoxylin and eosin staining showed hyperkeratosis of the skin as well as inflammatory and edematous changes. A diagnosis of a variant of FOT was made.<br />Interventions: We removed skin abscesses and lesioned the inner part with hydrogen peroxide. Then we performed an excision of the scrotal lesion.<br />Outcome: The patient recovered well and had no evidence of recurrence at a 16-month follow-up.<br />Lessons: We reported a case in which scrotal elephantiasis was a variant of FOT and surgical intervention played an important role in secondary urologic diseases.
- Subjects :
- Acne Conglobata genetics
Adult
Cellulitis genetics
Elephantiasis genetics
Elephantiasis pathology
Elephantiasis surgery
Hidradenitis Suppurativa genetics
Humans
Magnetic Resonance Imaging
Male
Scalp Dermatoses genetics
Skin Diseases, Genetic genetics
Acne Conglobata complications
Cellulitis complications
Elephantiasis etiology
Hidradenitis Suppurativa complications
Scalp Dermatoses complications
Scrotum diagnostic imaging
Scrotum pathology
Scrotum surgery
Skin Diseases, Genetic complications
Subjects
Details
- Language :
- English
- ISSN :
- 1536-5964
- Volume :
- 98
- Issue :
- 16
- Database :
- MEDLINE
- Journal :
- Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 31008968
- Full Text :
- https://doi.org/10.1097/MD.0000000000015263