Exome sequencing and pathogenicity-network analysis of five French families implicate mTOR signalling and autophagy in familial sarcoidosis.

Competing Interests: Conflict of interest: A. Calender has nothing to disclose. Conflict of interest: C.X. Lim has nothing to disclose. Conflict of interest: T. Weichhart has nothing to disclose. Conflict of interest: A. Buisson has nothing to disclose. Conflict of interest: V. Besnard has nothing to disclose. Conflict of interest: P.A. Rollat-Farnier has nothing to disclose. Conflict of interest: C. Bardel has nothing to disclose. Conflict of interest: P. Roy has nothing to disclose. Conflict of interest: V. Cottin reports personal fees for lecturing and consultancy, and non-financial support for travel from Actelion, grants, personal fees for development of educational material, lecturing and consultancy, and non-financial support for travel from Boehringer Ingelheim, personal fees for consultancy from Bayer/MSD, GSK and Galapagos, personal fees for adjudication board work from Gilead, personal fees for lecturing and consultancy from Novartis, grants, personal fees for lecturing and consultancy, and non-financial support for travel from Roche, grants from Sanofi, personal fees for data monitoring committee work from Promedior and Celgene, outside the submitted work. Conflict of interest: G. Devouassoux has nothing to disclose. Conflict of interest: A. Finat has nothing to disclose. Conflict of interest: S. Pinson has nothing to disclose. Conflict of interest: S. Lebecque has nothing to disclose. Conflict of interest: H. Nunes reports grants and personal fees for consultancy from Roche/Genentech and Boehringer Ingelheim, and has acted as an investigator in a clinical trial for Sanofi and Gilead, outside the submitted work. Conflict of interest: D. Israel-Biet has nothing to disclose. Conflict of interest: A. Bentaher has nothing to disclose. Conflict of interest: D. Valeyre reports personal fees for advisory board work from Boehringer Ingelheim and Roche, personal fees for lecturing from AstraZeneca, financial support for transportation and accommodation related to scientific meetings from Boehringer Ingelheim and Roche, outside the submitted work. Conflict of interest: Y. Pacheco has nothing to disclose.