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Current Immunotherapy Practices in Melanoma.

Authors :
Rothermel LD
Sarnaik AA
Khushalani NI
Sondak VK
Source :
Surgical oncology clinics of North America [Surg Oncol Clin N Am] 2019 Jul; Vol. 28 (3), pp. 403-418. Date of Electronic Publication: 2019 Apr 12.
Publication Year :
2019

Abstract

Immunotherapy has revolutionized the treatment of melanoma, with implications for the surgical management of this disease. Surgeons must be aware of the impact of various immunotherapies on patients with resectable and unresectable disease, and how surgical decision-making should progress as a result. We expect that current and developing immunotherapies will increase surgeon involvement for resection of metastatic melanoma, whether for tumor harvests to generate autologous lymphocytes or for consolidating control of disease beyond what immunotherapies alone can achieve. Despite remarkable advancements in the field, significant work is needed to optimize the immuno-modulation that targets cancers while minimizing toxicity for patients.<br /> (Copyright © 2019 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1558-5042
Volume :
28
Issue :
3
Database :
MEDLINE
Journal :
Surgical oncology clinics of North America
Publication Type :
Academic Journal
Accession number :
31079796
Full Text :
https://doi.org/10.1016/j.soc.2019.02.001