Back to Search
Start Over
[Pathogenic mechanisms of Tick-borne Flaviviruses].
- Source :
-
Uirusu [Uirusu] 2018; Vol. 68 (1), pp. 78-88. - Publication Year :
- 2018
-
Abstract
- Many tick-borne flaviviruses causes fatal encephalitis in humans and animals with severe sequelae. However, it remains unclear how viral replication and pathogenicity contribute to the neurologic manifestations. In this paper, I summarized the specific replication mechanism of tick-borne flaviviruses in neurons and their effect on the pathogenicity of neurological disease. Our findings of the unique virus-host interaction in central nerve system will improve further understanding of the molecular mechanisms of viral replication and the pathogenicity of neurotropic viruses.
- Subjects :
- Amino Acids
Animals
Antigens, Viral metabolism
Disease Models, Animal
Encephalitis, Viral virology
Flavivirus genetics
Flavivirus immunology
Host-Pathogen Interactions
Humans
Mice
Neurites virology
Neurons virology
Rats
Viral Nonstructural Proteins chemistry
Central Nervous System virology
Flavivirus pathogenicity
Flavivirus physiology
Flavivirus Infections virology
Ticks virology
Viral Nonstructural Proteins physiology
Virus Replication
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0042-6857
- Volume :
- 68
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Uirusu
- Publication Type :
- Academic Journal
- Accession number :
- 31105138
- Full Text :
- https://doi.org/10.2222/jsv.68.78