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Advances and potential application of gold nanoparticles in nanomedicine.

Authors :
Lopes TS
Alves GG
Pereira MR
Granjeiro JM
Leite PEC
Source :
Journal of cellular biochemistry [J Cell Biochem] 2019 Oct; Vol. 120 (10), pp. 16370-16378. Date of Electronic Publication: 2019 May 24.
Publication Year :
2019

Abstract

Nanomedicine is an emerging research area which has brought new possibilities and promising applications in image, diagnosis, and treatment. Nanoparticles (NPs) for medicinal purposes can be made of several material types such as silica, carbon, different polymers, and metals as silver, copper, titanium, and gold. Gold NPs (AuNPs) are the most studied and used, mostly due to their characteristics including simple preparation, controllable size and distribution, biocompatibility, good acceptance of surface modifications, and specific surface plasmon resonance (SPR). This study reviews the scientific literature regarding the potential applications of AuNPs in the development of new diagnostic and therapeutic strategies for nanomedicine, including their biomedical use as a drug carrier, as an agent in radio and phototherapy, and bioimaging for image diagnosis. While it becomes clear that much research remains to be done to improve the use of these nanoparticles, with particular concern for safety issues, the evidence from the literature already points to the great potential of AuNPs in nanomedicine.<br /> (© 2019 Wiley Periodicals, Inc.)

Details

Language :
English
ISSN :
1097-4644
Volume :
120
Issue :
10
Database :
MEDLINE
Journal :
Journal of cellular biochemistry
Publication Type :
Academic Journal
Accession number :
31127662
Full Text :
https://doi.org/10.1002/jcb.29044