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Ceftriaxone-resistant Salmonella enterica serotype Typhi in a pregnant traveller returning from Karachi, Pakistan to Denmark, 2019.
- Source :
-
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin [Euro Surveill] 2019 May; Vol. 24 (21). - Publication Year :
- 2019
-
Abstract
- We describe a ceftriaxone-resistant Salmonella Typhi bacteraemia in a pregnant woman returning from a family visit in Pakistan. Whole genome sequencing confirmed similarity to a Pakistani outbreak clone. Pregnancy and unawareness of this outbreak delayed appropriate antibiotic therapy. Concurrently, we detected faecal carriage of a carbapenemase-producing Escherichia coli. Awareness of the ongoing outbreak should affect empiric treatment of typhoid fever and hygiene precautions in travellers returning from Pakistan. Meropenem may be warranted in severe cases.
- Subjects :
- Abdominal Pain etiology
Adult
Agglutination Tests
Anti-Bacterial Agents pharmacology
Bacteremia drug therapy
Carbapenem-Resistant Enterobacteriaceae
Ceftriaxone therapeutic use
Denmark
Drug Resistance
Escherichia coli genetics
Escherichia coli isolation & purification
Female
Fever etiology
Humans
Microbial Sensitivity Tests
Pakistan
Plasmids analysis
Polymerase Chain Reaction
Pregnancy
Salmonella typhi drug effects
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Travel
Typhoid Fever microbiology
Whole Genome Sequencing
Anti-Bacterial Agents therapeutic use
Azithromycin therapeutic use
Ceftriaxone pharmacology
Meropenem therapeutic use
Salmonella typhi genetics
Salmonella typhi isolation & purification
Typhoid Fever diagnosis
Typhoid Fever drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1560-7917
- Volume :
- 24
- Issue :
- 21
- Database :
- MEDLINE
- Journal :
- Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
- Publication Type :
- Academic Journal
- Accession number :
- 31138366
- Full Text :
- https://doi.org/10.2807/1560-7917.ES.2019.24.21.1900289