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Increasing Povidone-Iodine Exposure in Endothelial Keratoplasty Tissue Processing and Fungal Infection Impact.
- Source :
-
Cornea [Cornea] 2019 Sep; Vol. 38 (9), pp. 1093-1096. - Publication Year :
- 2019
-
Abstract
- Purpose: To evaluate the effect on donor rim cultures and postoperative infections of doubling the povidone-iodine exposure time during corneal tissue recovery before its use in keratoplasty.<br />Methods: Consecutive donor cornea recoveries were evaluated for positive donor corneal rim cultures and postoperative infections before and after a protocol change of doubling the exposure time of povidone-iodine during donor preparation.<br />Results: In 631 consecutive cornea donor recoveries, 18 (2.9%) had positive fungal rim cultures and 41 (6.5%) had positive bacterial rim cultures. Three (0.48%) developed postoperative fungal infections, and no bacterial infections occurred. After doubling the povidone-iodine exposure time during the recovery process, 725 consecutive corneas were reviewed. Four (0.6%) had positive fungal rim cultures, and 29 (4.0%) had positive bacterial rim cultures. No postoperative fungal or bacterial infections occurred. No noticeable increase in epithelial toxicity developed between the 2 groups.<br />Conclusions: Increasing the povidone-iodine exposure time during the donor cornea recovery process decreased the rate of positive donor corneal rim fungal cultures (P = 0.001), positive donor corneal rim bacterial cultures (P = 0.04), and postoperative fungal infections (P = 0.06).
- Subjects :
- Eye Infections, Bacterial prevention & control
Humans
Postoperative Complications prevention & control
Anti-Infective Agents, Local administration & dosage
Corneal Transplantation methods
Eye Infections, Fungal prevention & control
Povidone-Iodine administration & dosage
Tissue and Organ Harvesting methods
Subjects
Details
- Language :
- English
- ISSN :
- 1536-4798
- Volume :
- 38
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Cornea
- Publication Type :
- Academic Journal
- Accession number :
- 31169604
- Full Text :
- https://doi.org/10.1097/ICO.0000000000002006