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Parvoviral infection with systemic impact and renal consequences.
- Source :
-
BMJ case reports [BMJ Case Rep] 2019 Jun 08; Vol. 12 (6). Date of Electronic Publication: 2019 Jun 08. - Publication Year :
- 2019
-
Abstract
- Parvovirus infection is usually asymptomatic especially in immunocompetent adults. When symptomatic it can range from mild to life threatening depending on the patient's age and comorbidities. We report a case of a 40-year-old male patient with parvovirus infection who presented a purpuric rash in distal extremities, acute kidney injury, type II mixed cryoglobulinaemia and hypocomplementaemia. His renal biopsy showed a mesangioproliferative glomerulonephritis with positive immunoreactivity to C3, IgM and C1q. Parvovirus B19 was detected in the biopsy tissue by PCR. He was treated with prednisolone with total remission after 1 month. We discuss the diagnosis of kidney lesion due to parvovirus in an immunocompetent person, which is a very rare condition and its association with the cryoglobulinaemia diagnosis.<br />Competing Interests: Competing interests: None declared.<br /> (© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.)
- Subjects :
- Adult
Glomerulonephritis, Membranoproliferative diagnostic imaging
Glomerulonephritis, Membranoproliferative drug therapy
Humans
Male
Parvoviridae Infections drug therapy
Parvovirus B19, Human isolation & purification
Treatment Outcome
Glomerulonephritis, Membranoproliferative virology
Parvoviridae Infections diagnosis
Prednisolone therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1757-790X
- Volume :
- 12
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- BMJ case reports
- Publication Type :
- Academic Journal
- Accession number :
- 31177196
- Full Text :
- https://doi.org/10.1136/bcr-2019-229622