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Effect of In Vitro Digestion on Phytochemical Profiles and Cellular Antioxidant Activity of Whole Grains.
- Source :
-
Journal of agricultural and food chemistry [J Agric Food Chem] 2019 Jun 26; Vol. 67 (25), pp. 7016-7024. Date of Electronic Publication: 2019 Jun 13. - Publication Year :
- 2019
-
Abstract
- Most of the previous in vitro digestion treatments were conducted directly to whole grains without extraction of free phenolics, thus the bioaccessible phenolics contained both free phenolics that survived the digestion and digested phenolics released by digestion. However, the profiles of digested phenolics released by digestion remain unknown. This study was designed to investigate the phytochemical contents, peroxyl radical scavenging capacities (PSCs), and cellular antioxidant activities (CAAs) of free, digested, and bound fractions of whole grains. Total phenolic contents of whole grains were highest in digested fraction, followed by free and bound fractions. The predominant phenolics were 12 phenolic acids and one flavonoid, which mostly existed in bound forms, then in digested and free forms. The digested phenolics bound to proteins were in conjugated form. The bound fractions had the highest PSCs, followed by free and digested fractions. CAAs were highest in bound fractions, followed by digested and free fractions.
- Subjects :
- Antioxidants chemistry
Cell Line
Digestion
Flavonoids chemistry
Flavonoids metabolism
Hep G2 Cells
Humans
Models, Biological
Phenols chemistry
Phenols metabolism
Phytochemicals chemistry
Plant Extracts chemistry
Seeds chemistry
Seeds metabolism
Antioxidants metabolism
Phytochemicals metabolism
Plant Extracts metabolism
Whole Grains metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1520-5118
- Volume :
- 67
- Issue :
- 25
- Database :
- MEDLINE
- Journal :
- Journal of agricultural and food chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 31194907
- Full Text :
- https://doi.org/10.1021/acs.jafc.9b02245