Pattern of failure after adjuvant radiotherapy following extrapleural pneumonectomy of pleural mesothelioma in the SAKK 17/04 trial.

Authors :: Riesterer O
Ciernik IF
Stahel RA
Xyrafas A
Aebersold DM
Plasswilm L
Mahmut Ozsahin E
Zwahlen DR
Nackaerts K
Zimmermann F
Sabrina Stark L
Weder W
Krayenbuehl J
Source :: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2019 Sep; Vol. 138, pp. 121-125. Date of Electronic Publication: 2019 Jun 25.
Publication Year :: 2019
Abstract: Postoperative radiotherapy after extrapleural pneumonectomy of malignant pleural mesothelioma was investigated in the randomized phase II trial SAKK17/04. The relapse rate within the high and/or low-dose PTV without previous distant failure was 24%, the isolated in-field-relapse rate within the PTVs was 5% and the distant relapse rate outside of the PTVs was 81%. Clinical outcome was mainly determined by distant disease progression outside of the radiation field.<br /> (Copyright © 2019 Elsevier B.V. All rights reserved.)

Language :: English
ISSN :: 1879-0887
Volume :: 138
Database :: MEDLINE
Journal :: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Publication Type :: Academic Journal
Accession number :: 31252293
Full Text :: https://doi.org/10.1016/j.radonc.2019.05.024

Full Text Access

Tools