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A non-randomized trial of conversion from ciclosporin and tacrolimus to tacrolimus MR4 in stable long-term kidney transplant recipients: Graft function and influences of ABCB1 genotypes.
- Source :
-
PloS one [PLoS One] 2019 Jul 02; Vol. 14 (7), pp. e0218709. Date of Electronic Publication: 2019 Jul 02 (Print Publication: 2019). - Publication Year :
- 2019
-
Abstract
- Trial Registration: PEP Study: Ethics committee N° 393/2004, EudraCT 2004-004209-98. PEP-X Study: Ethics committee amendment application N° 154/01/2008. ClinicalTrials.gov NCT03751332.<br />Competing Interests: This commercial affiliation (in the form of salaries from Astellas Pharma Inc. for MP, research/travel funds for MR, and an unrestricted grant for GSP) does not alter our adherence to PLOS ONE policies on sharing data and materials. There are no other relevant declarations relating to employment, consultancy, patents, products in development, or marketed products.
- Subjects :
- ATP Binding Cassette Transporter, Subfamily B genetics
Aged
Biopsy
Cyclosporine adverse effects
Female
Genetic Association Studies
Genotype
Glomerular Filtration Rate physiology
Graft Rejection genetics
Graft Rejection physiopathology
Humans
Immunosuppressive Agents administration & dosage
Male
Middle Aged
Tacrolimus adverse effects
Tissue Donors
Cyclosporine administration & dosage
Graft Rejection drug therapy
Kidney Transplantation adverse effects
Tacrolimus administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1932-6203
- Volume :
- 14
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- PloS one
- Publication Type :
- Academic Journal
- Accession number :
- 31266056
- Full Text :
- https://doi.org/10.1371/journal.pone.0218709