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Screening and Prophylaxis to Prevent Hepatitis B Reactivation: Introduction and Immunology.
- Source :
-
Clinics in liver disease [Clin Liver Dis] 2019 Aug; Vol. 23 (3), pp. 487-492. Date of Electronic Publication: 2019 Jun 06. - Publication Year :
- 2019
-
Abstract
- Current recommendations concerning hepatitis C virus (HBV) reactivation are limited, with nearly all guidelines focused on its occurrence in patients with hematological malignancies or some solid tumors, who are treated with immunosuppressive therapies. Few of the guidelines address reactivation in patients receiving immunosuppression with organ transplants or treatment with any of the many immunosuppressive agents in use today for the treatment of multiple different diseases, or in patients receiving the direct-acting antivirals used in the treatment of hepatitis C virus (HCV). This article covers the immunology of HBV reactivation, mechanisms of viral clearance, and recommendations for screening and prophylaxis.<br /> (Copyright © 2019 Elsevier Inc. All rights reserved.)
- Subjects :
- Adaptive Immunity drug effects
Female
Hepatitis B physiopathology
Humans
Immunity, Innate drug effects
Male
Mass Screening methods
Primary Prevention
Prognosis
Risk Assessment
Adaptive Immunity immunology
Hepatitis B virology
Hepatitis B virus physiology
Immunity, Innate immunology
Immunosuppressive Agents therapeutic use
Virus Activation immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1557-8224
- Volume :
- 23
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Clinics in liver disease
- Publication Type :
- Academic Journal
- Accession number :
- 31266622
- Full Text :
- https://doi.org/10.1016/j.cld.2019.04.009