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Cocaine in Hospital Admissions for Diseases of the Circulatory System and as the Underlying Cause of Death: Analysis and Discussion.
- Source :
-
Cardiovascular toxicology [Cardiovasc Toxicol] 2020 Feb; Vol. 20 (1), pp. 20-27. - Publication Year :
- 2020
-
Abstract
- Cocaine is a cardiotoxic drug which has been associated with morbi-mortality due to cardiovascular diseases (CVD). This study aims to: (1) analyze the hospitalizations due to cardiovascular processes and the presence of cocaine among the toxic habits of patients; and (2) discuss the forensic difficulties in sudden cardiac death (SCD) in the presence of cocaine. Hospital discharges due to CVD reporting cocaine consumption as a secondary diagnosis between 2003 and 2013 in Spain were analyzed. Subsequently, a review of judicial autopsies (SCD in cocaine users) was carried out to illustrate the forensic difficulties in the determination of the manner and underlying cause of death when cocaine use is involved. The average CVD morbidity rate was 1104.4 per 100,000 population. The most common main diagnoses of which cocaine use was recorded as a secondary diagnosis were rheumatic fever, ischemic heart disease and cerebrovascular disease in male patients between 15 and 44 years. The cardiovascular findings in the autopsies of cocaine users vary, and determining the mechanism that triggered the death in forensic practice is a challenge. The presence of cocaine among the toxic habits of young patients admitted for CVD in Spain is increasing. In our opinion, criteria must be unified to establish the manner and underlying cause of death in SCD and toxicological analysis can be a key part in the process.
- Subjects :
- Adolescent
Adult
Aged
Autopsy
Cardiotoxicity
Cardiovascular Diseases diagnosis
Cause of Death
Child
Child, Preschool
Cocaine-Related Disorders diagnosis
Databases, Factual
Female
Forensic Toxicology
Humans
Incidence
Infant
Infant, Newborn
Male
Middle Aged
Risk Assessment
Risk Factors
Spain epidemiology
Young Adult
Cardiovascular Diseases mortality
Cocaine-Related Disorders mortality
Death, Sudden, Cardiac epidemiology
Patient Admission
Subjects
Details
- Language :
- English
- ISSN :
- 1559-0259
- Volume :
- 20
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Cardiovascular toxicology
- Publication Type :
- Academic Journal
- Accession number :
- 31273689
- Full Text :
- https://doi.org/10.1007/s12012-019-09537-6