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Incidental Detection of a Radiation-Induced Soft-Tissue Sarcoma on 68Ga-PSMA PET/CT in a Patient Previously Treated for Prostate Cancer.
- Source :
-
Clinical nuclear medicine [Clin Nucl Med] 2019 Aug; Vol. 44 (8), pp. e501-e502. - Publication Year :
- 2019
-
Abstract
- Radiation-induced sarcoma is a rare complication of radiation therapy. We describe the incidental detection of a radiation-induced undifferentiated soft-tissue sarcoma with increased uptake on Ga-labeled prostate-specific membrane antigen (PSMA) PET/CT in a prostate cancer patient previously treated with surgery and external-beam radiotherapy. Results were confirmed by histological analysis. Ga-PSMA is known to bind not only to PSMA-expressing prostate cancer cells but also to the neovasculature of various other solid tumors. A careful Ga-PSMA PET/CT review of previously irradiated areas is warranted so as not to miss radiation-induced sarcoma in prostate cancer patients.
- Subjects :
- Aged
Gallium Isotopes
Gallium Radioisotopes
Humans
Male
Neoplasms, Radiation-Induced etiology
Soft Tissue Neoplasms etiology
Incidental Findings
Membrane Glycoproteins
Neoplasms, Radiation-Induced diagnostic imaging
Organometallic Compounds
Positron Emission Tomography Computed Tomography
Prostatic Neoplasms radiotherapy
Soft Tissue Neoplasms diagnostic imaging
Subjects
Details
- Language :
- English
- ISSN :
- 1536-0229
- Volume :
- 44
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Clinical nuclear medicine
- Publication Type :
- Academic Journal
- Accession number :
- 31274636
- Full Text :
- https://doi.org/10.1097/RLU.0000000000002592