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Serum beta 2-microglobulin in patients with monoclonal gammopathies.

Authors :
Di Giovanni S
Valentini G
Ravazzolo E
Carducci P
Giallonardo P
Maschio C
Source :
The International journal of biological markers [Int J Biol Markers] 1987 Sep-Dec; Vol. 2 (3), pp. 169-72.
Publication Year :
1987

Abstract

Beta-2-microglobulin concentrations were determined in serum samples from 45 patients with benign and malignant monoclonal gammopathies. In the group of patients suffering from multiple myeloma or Waldenström macroglobulinemia the mean beta 2-microglobulin level was significantly higher than in the group with monoclonal gammopathy of undetermined significance. Values above 3 mg/L were highly indicative of a neoplastic process and were observed in all the Waldenström patients and in greater than 90% of myeloma patients. No significant correlation was noticed between beta 2-microglobulin and monoclonal protein levels in any of the groups examined.

Details

Language :
English
ISSN :
0393-6155
Volume :
2
Issue :
3
Database :
MEDLINE
Journal :
The International journal of biological markers
Publication Type :
Academic Journal
Accession number :
3131451