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Identification of novel mutations and phenotype in the steroid resistant nephrotic syndrome gene NUP93: a case report.

Authors :
Sandokji I
Marquez J
Ji W
Zerillo CA
Konstantino M
Lakhani SA
Khokha MK
Warejko JK
Source :
BMC nephrology [BMC Nephrol] 2019 Jul 17; Vol. 20 (1), pp. 271. Date of Electronic Publication: 2019 Jul 17.
Publication Year :
2019

Abstract

Background: Monogenic mutations may be a significant cause of steroid-resistant nephrotic syndrome. NUP93 is a gene previously reported to cause isolated steroid-resistant nephrotic syndrome.<br />Case Presentation: Here we describe a case of recessive, syndromic, steroid-resistant nephrotic syndrome caused by NUP93 mutation.<br />Conclusions: NUP93 may convey a phenotype that has not only SRNS, but also other syndromic features.

Details

Language :
English
ISSN :
1471-2369
Volume :
20
Issue :
1
Database :
MEDLINE
Journal :
BMC nephrology
Publication Type :
Academic Journal
Accession number :
31315584
Full Text :
https://doi.org/10.1186/s12882-019-1458-z