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A Case of Pulmonary Veno-occlusive Disease Following Hepatic Veno-occlusive Disease After Autologous Hematopoietic Stem Cell Transplantation for Neuroblastoma.

Authors :
Isshiki K
Shima H
Yamazaki F
Takenouchi T
Shimada H
Source :
Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2020 Oct; Vol. 42 (7), pp. e677-e679.
Publication Year :
2020

Abstract

Pulmonary veno-occlusive disease (PVOD) is an uncommon form of pulmonary hypertension that is usually difficult to diagnose and is refractory to conservative treatment. PVOD can occur in connection with high-dose chemotherapy or hematopoietic stem cell transplantation, similar to hepatic veno-occlusive disease (HVOD). Here, we present a case of neuroblastoma with PVOD following HVOD after high-dose chemotherapy that was resolved with conservative treatment. Respiratory symptoms or edema after HVOD may suggest PVOD, and prompt diagnosis on high-resolution computed tomography will result in a favorable prognosis.

Details

Language :
English
ISSN :
1536-3678
Volume :
42
Issue :
7
Database :
MEDLINE
Journal :
Journal of pediatric hematology/oncology
Publication Type :
Academic Journal
Accession number :
31335821
Full Text :
https://doi.org/10.1097/MPH.0000000000001566