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A Case of Pulmonary Veno-occlusive Disease Following Hepatic Veno-occlusive Disease After Autologous Hematopoietic Stem Cell Transplantation for Neuroblastoma.
- Source :
-
Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2020 Oct; Vol. 42 (7), pp. e677-e679. - Publication Year :
- 2020
-
Abstract
- Pulmonary veno-occlusive disease (PVOD) is an uncommon form of pulmonary hypertension that is usually difficult to diagnose and is refractory to conservative treatment. PVOD can occur in connection with high-dose chemotherapy or hematopoietic stem cell transplantation, similar to hepatic veno-occlusive disease (HVOD). Here, we present a case of neuroblastoma with PVOD following HVOD after high-dose chemotherapy that was resolved with conservative treatment. Respiratory symptoms or edema after HVOD may suggest PVOD, and prompt diagnosis on high-resolution computed tomography will result in a favorable prognosis.
- Subjects :
- Child, Preschool
Combined Modality Therapy
Female
Hepatic Veno-Occlusive Disease etiology
Humans
Neuroblastoma pathology
Prognosis
Pulmonary Veno-Occlusive Disease etiology
Transplantation, Autologous
Antineoplastic Combined Chemotherapy Protocols adverse effects
Hematopoietic Stem Cell Transplantation adverse effects
Hepatic Veno-Occlusive Disease pathology
Neuroblastoma therapy
Pulmonary Veno-Occlusive Disease pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1536-3678
- Volume :
- 42
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Journal of pediatric hematology/oncology
- Publication Type :
- Academic Journal
- Accession number :
- 31335821
- Full Text :
- https://doi.org/10.1097/MPH.0000000000001566