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Thyroid-Like Follicular Renal Cell Carcinoma Arising Within Benign Mixed Epithelial and Stromal Tumor.
- Source :
-
International journal of surgical pathology [Int J Surg Pathol] 2020 Feb; Vol. 28 (1), pp. 80-86. Date of Electronic Publication: 2019 Jul 25. - Publication Year :
- 2020
-
Abstract
- Thyroid-like follicular renal cell carcinoma (TLF-RCC) is an extremely rare tumor with less than 40 published reports. These tumors are morphologically distinct with striking resemblance to thyroid follicular tumors, but immunohistochemically different due to lack of thyroglobulin and thyroid transcription factor 1 expression. TLF-RCCs arise in younger patients (mean age = 41 years) with female predominance and in all reported cases were solitary tumors without coexisting epithelial or mesenchymal kidney neoplasms. In this article, we report a case of a 42-year-old woman who presented with an incidental 4-cm solid and cystic left renal mass of the upper pole, which was resected. A detailed imaging assessment, pathologic findings, and immunohistochemical studies revealed a partially encapsulated TLF-RCC arising in a background of mixed epithelial and stromal tumor.
- Subjects :
- Adenocarcinoma, Follicular pathology
Adult
Carcinoma, Renal Cell diagnosis
Female
Humans
Kidney Neoplasms diagnosis
Neoplasms, Complex and Mixed diagnosis
Neoplasms, Glandular and Epithelial diagnosis
Thyroid Neoplasms pathology
Carcinoma, Renal Cell pathology
Kidney Neoplasms pathology
Neoplasms, Complex and Mixed pathology
Neoplasms, Glandular and Epithelial pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1940-2465
- Volume :
- 28
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- International journal of surgical pathology
- Publication Type :
- Academic Journal
- Accession number :
- 31342803
- Full Text :
- https://doi.org/10.1177/1066896919863478