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Pheochromocytoma and Pregnancy.

Authors :
Lenders JWM
Langton K
Langenhuijsen JF
Eisenhofer G
Source :
Endocrinology and metabolism clinics of North America [Endocrinol Metab Clin North Am] 2019 Sep; Vol. 48 (3), pp. 605-617. Date of Electronic Publication: 2019 Jun 13.
Publication Year :
2019

Abstract

Pheochromocytoma during pregnancy, although rare, is a perilous condition. The wellbeing of mother and fetus are at stake if not diagnosed and treated antenatally and timely. The diagnosis is frequently overlooked because of the aspecific nature of signs and symptoms and confusion with pregnancy-related hypertension. Measurements of plasma or urinary free metanephrines have the highest diagnostic accuracy. MRI is preferred over ultrasonography. The optimal time for surgical removal is before 24 weeks of gestation or at/after delivery. Laparoscopic adrenalectomy should be preceded by medical pretreatment. Cesarean delivery is preferred in these patients; vaginal delivery might be considered in selected pretreated patients.<br /> (Copyright © 2019 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1558-4410
Volume :
48
Issue :
3
Database :
MEDLINE
Journal :
Endocrinology and metabolism clinics of North America
Publication Type :
Academic Journal
Accession number :
31345526
Full Text :
https://doi.org/10.1016/j.ecl.2019.05.006