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[Osteoporosis and chronic kidney disease: review and new therapeutic strategies].
- Source :
-
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia [G Ital Nefrol] 2019 Jul 24; Vol. 36 (4). Date of Electronic Publication: 2019 Jul 24. - Publication Year :
- 2019
-
Abstract
- Osteoporosis affects a segment of the population in which Chronic Kidney Disease is also greatly represented. Nephropathic patients may present peculiar biochemical abnormalities related to Chronic Kidney Disease, defining the Mineral and Bone Disorder. This kind of anomalies, in the worst scenarios, configure the typical histomorphology patterns of Renal Osteodystrophy. Scientific Societies of Endocrinology have established therapy guidelines for patients with osteoporosis only based on the glomerular filtration rate and recommend avoiding the use of some drugs for the more advanced classes of nephropathy. However, there is no clear therapeutic approach for patients with advanced nephropathy and bone abnormalities. In this paper we propose a systematic review of the literature and present our proposal for managing patients with advanced nephropathy, based on eGFR and on presence of Mineral and Bone Disorder.<br /> (Copyright by Società Italiana di Nefrologia SIN, Rome, Italy.)
- Subjects :
- Antibodies, Monoclonal therapeutic use
Bone Density Conservation Agents adverse effects
Bone Density Conservation Agents chemistry
Chronic Kidney Disease-Mineral and Bone Disorder etiology
Chronic Kidney Disease-Mineral and Bone Disorder physiopathology
Contraindications
Denosumab therapeutic use
Diphosphonates adverse effects
Diphosphonates chemistry
Female
Fractures, Spontaneous drug therapy
Fractures, Spontaneous etiology
Fractures, Spontaneous prevention & control
Glomerular Filtration Rate
Humans
Male
Osteoporosis complications
Osteoporosis diagnosis
Parathyroid Hormone-Related Protein therapeutic use
Practice Guidelines as Topic
Renal Insufficiency, Chronic physiopathology
Risk Factors
Teriparatide therapeutic use
Bone Density Conservation Agents therapeutic use
Chronic Kidney Disease-Mineral and Bone Disorder drug therapy
Diphosphonates therapeutic use
Osteoporosis drug therapy
Renal Insufficiency, Chronic complications
Subjects
Details
- Language :
- Italian
- ISSN :
- 1724-5990
- Volume :
- 36
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia
- Publication Type :
- Academic Journal
- Accession number :
- 31373465