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Toxoplasmosis as an Early Complication of Allogeneic Hematopoietic Cell Transplantation.
- Source :
-
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation [Biol Blood Marrow Transplant] 2019 Dec; Vol. 25 (12), pp. 2510-2513. Date of Electronic Publication: 2019 Aug 02. - Publication Year :
- 2019
-
Abstract
- Among 419 consecutive allogeneic hematopoietic cell transplant recipients, we observed 17 (4.0%) cases of toxoplasmosis at a median time of day 45 (range, 6 to 322) after transplant. Seven of these 17 cases occurred before day 30 after transplant. Because of the lack of PCR screening and trimethoprim-sulfamethoxazole prophylaxis before engraftment, the diagnosis of toxoplasmosis was late, and 5 of these 7 patients died. Analyzing these cases, early Toxoplasma blood PCR screening, starting from transplant, is crucial.<br /> (Copyright © 2019 American Society for Transplantation and Cellular Therapy. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Adult
Aged
Allografts
Female
France epidemiology
Humans
Incidence
Male
Middle Aged
Hematopoietic Stem Cell Transplantation
Toxoplasmosis diagnosis
Toxoplasmosis etiology
Toxoplasmosis mortality
Toxoplasmosis prevention & control
Trimethoprim, Sulfamethoxazole Drug Combination administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1523-6536
- Volume :
- 25
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
- Publication Type :
- Academic Journal
- Accession number :
- 31381996
- Full Text :
- https://doi.org/10.1016/j.bbmt.2019.07.035