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Effect of ethanol/TEOS ratios and amount of ammonia on the properties of copper-doped calcium silicate nanoceramics.
- Source :
-
Journal of materials science. Materials in medicine [J Mater Sci Mater Med] 2019 Aug 22; Vol. 30 (9), pp. 98. Date of Electronic Publication: 2019 Aug 22. - Publication Year :
- 2019
-
Abstract
- Calcium magnesium silicate glasses could be suggested for the synthesis of scaffolds for hard tissue regeneration, as they present a high residual glassy phase, high hardness values and hydroxyapatite-forming ability. The use of trace elements in the human body, such as Cu, could improve the biological performance of such glasses, as Cu is known to play a significant role in angiogenesis. Nano-bioceramics are preferable compared to their micro-scale counterparts, because of their increased surface area, which improves both mechanical properties and apatite-forming ability due to the increased nucleation sites provided, their high diffusion rates, reduced sintering time or temperature, and high mechanical properties. The aim of the present work was the evaluation of the effect of different ratios of Ethanol/TEOS and total amount of the inserted ammonia to the particle size, morphology and bioactive, hemolytic and antibacterial behavior of nanoparticles in the quaternary system SiO <subscript>2</subscript> -CaO-MgO-CuO. Different ratios of Ethanol/TEOS and ammonia amount affected the size and morphology of bioactive nanopowders. The optimum materials were synthesized with the highest ethanol/TEOS ratio and ammonia amount as verified by the enhanced apatite-forming ability and antibacterial and non-hemolytic properties.
- Subjects :
- Apatites chemical synthesis
Apatites chemistry
Biocompatible Materials chemical synthesis
Biocompatible Materials chemistry
Ceramics chemical synthesis
Ceramics chemistry
Dose-Response Relationship, Drug
Erythrocytes cytology
Erythrocytes drug effects
Ethanol chemistry
Glass chemistry
Humans
Materials Testing
Nanocomposites chemistry
Silicates chemistry
Silicates pharmacology
Silicon Dioxide chemistry
Surface Properties drug effects
Ammonia pharmacology
Calcium chemistry
Copper chemistry
Ethanol pharmacology
Silicates chemical synthesis
Subjects
Details
- Language :
- English
- ISSN :
- 1573-4838
- Volume :
- 30
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Journal of materials science. Materials in medicine
- Publication Type :
- Academic Journal
- Accession number :
- 31440844
- Full Text :
- https://doi.org/10.1007/s10856-019-6297-8