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Tiny Dancer: EFCAB9 Triggers Sperm Hyperactivation via CatSper.
- Source :
-
Trends in biochemical sciences [Trends Biochem Sci] 2019 Oct; Vol. 44 (10), pp. 823-826. Date of Electronic Publication: 2019 Aug 22. - Publication Year :
- 2019
-
Abstract
- The Ca <superscript>2+</superscript> -conducting ion channel, CatSper, is expressed exclusively on the sperm flagellum and regulates sperm motility. A new study (Hwang et al., Cell, 2019) reveals that the pH-sensing and Ca <superscript>2+</superscript> -binding protein, EFCAB9, is a subunit of the CatSper channel and has a key role in triggering mammalian sperm to change their swimming at fertilization.<br /> (Copyright © 2019 Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 0968-0004
- Volume :
- 44
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Trends in biochemical sciences
- Publication Type :
- Academic Journal
- Accession number :
- 31447243
- Full Text :
- https://doi.org/10.1016/j.tibs.2019.08.001