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Minoxidil and its use in hair disorders: a review.
- Source :
-
Drug design, development and therapy [Drug Des Devel Ther] 2019 Aug 09; Vol. 13, pp. 2777-2786. Date of Electronic Publication: 2019 Aug 09 (Print Publication: 2019). - Publication Year :
- 2019
-
Abstract
- Minoxidil was first introduced as an antihypertensive medication and the discovery of its common adverse event, hypertrichosis, led to the development of a topical formulation for promoting hair growth. To date, topical minoxidil is the mainstay treatment for androgenetic alopecia and is used as an off-label treatment for other hair loss conditions. Despite its widespread application, the exact mechanism of action of minoxidil is still not fully understood. In this article, we aim to review and update current information on the pharmacology, mechanism of action, clinical efficacy, and adverse events of topical minoxidil.<br />Competing Interests: The authors report no conflicts of interest in this work.
- Subjects :
- Animals
Antihypertensive Agents administration & dosage
Antihypertensive Agents chemistry
Hair metabolism
Hair pathology
Humans
Hypertrichosis chemically induced
Minoxidil administration & dosage
Minoxidil chemistry
Molecular Structure
Sulfotransferases metabolism
Antihypertensive Agents pharmacology
Hair drug effects
Minoxidil pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 1177-8881
- Volume :
- 13
- Database :
- MEDLINE
- Journal :
- Drug design, development and therapy
- Publication Type :
- Academic Journal
- Accession number :
- 31496654
- Full Text :
- https://doi.org/10.2147/DDDT.S214907