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Case Report: Paracoccidioidomycosis in Solid Organ Transplantation: Disseminated Disease in a Liver Recipient and Literature Review.

Authors :
Peçanha-Pietrobom PM
Falqueto A
Rodrigues Gandarella AD
Moyzés JV
Rangel KA
Miranda LB
Hemerly MC
Careta RS
Peçanha PM
Source :
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2019 Nov; Vol. 101 (5), pp. 1100-1106.
Publication Year :
2019

Abstract

Paracoccidioidomycosis (PCM) is an endemic systemic mycosis that is of great importance in Latin America. Its occurrence in solid organ transplantation (SOT) is rare, but with high mortality rate. In this report, we describe a case of PCM in a liver transplant recipient 19 months after transplantation. The patient presented with multiple skin abscesses, arthritis, osteolytic lesions, and pulmonary and adrenal involvement. Despite the presence of disseminated disease and the patient's immunosuppressed condition, the patient responded well to prolonged antifungal treatment with no sequelae, thus suggesting that early diagnosis and correct treatment may lead to favorable outcomes in SOT recipients with PCM.

Details

Language :
English
ISSN :
1476-1645
Volume :
101
Issue :
5
Database :
MEDLINE
Journal :
The American journal of tropical medicine and hygiene
Publication Type :
Academic Journal
Accession number :
31516118
Full Text :
https://doi.org/10.4269/ajtmh.18-1008