Macular neurosensory retinal detachment associated with topiramate use.

Authors :: Muñoz Morales A
Sánchez-Vicente JL
Franco Ruedas C
de Las Morenas Iglesias J
Espiñeira Periñán MÁ
López-Herrero F
Source :: Archivos de la Sociedad Espanola de Oftalmologia [Arch Soc Esp Oftalmol (Engl Ed)] 2019 Dec; Vol. 94 (12), pp. 614-618. Date of Electronic Publication: 2019 Oct 11.
Publication Year :: 2019
Abstract: A 36 year-old woman with idiopathic intracranial hypertension was treated with topiramate and acetazolamide. The patient was followed-up for 2 years, with a relationship between neurosensory detachments and topiramate being established, with recurrences after the introduction of topiramato and improvement after its withdrawal. These findings point topiramate as a possible cause of the clinical picture. Topiramate may cause retinal and macular neurosensory detachments. Although the ciliochoroidal effusion cases caused by this drug are well-known, its retinal side effects are less common. As it is a widely used drug, neurologists and ophthalmologists should be aware of its possible ocular side effects.<br /> (Copyright © 2019 Sociedad Española de Oftalmología. Publicado por Elsevier España, S.L.U. All rights reserved.)