Recoding the metagenome: microbiome engineering in situ.

Authors :: Whitfill T
Oh J
Source :: Current opinion in microbiology [Curr Opin Microbiol] 2019 Aug; Vol. 50, pp. 28-34. Date of Electronic Publication: 2019 Oct 15.
Publication Year :: 2019
Abstract: Synthetic biology has enabled a new generation of tools for engineering the microbiome, including targeted antibiotics, protein delivery, living biosensors and diagnostics, and metabolic factories. Here, we discuss opportunities and limitations in microbiome engineering, focusing on a new generation of tools for in situ genetic modification of a microbiome that hold particular promise in circumventing these limitations.<br /> (Copyright © 2019 Elsevier Ltd. All rights reserved.)