In-vivo metabolic studies of regional adipose tissue.

Authors :: Melvin A
McQuaid SE
Source :: Cardiovascular endocrinology & metabolism [Cardiovasc Endocrinol Metab] 2018 Nov 14; Vol. 7 (4), pp. 75-79. Date of Electronic Publication: 2018 Nov 14 (Print Publication: 2018).
Publication Year :: 2018
Abstract: The accumulation of abdominal adipose tissue has long been associated with adverse cardiovascular outcomes. Paradoxically, increased gluteofemoral adipose tissue, which is predominantly subcutaneous fat, seems to play a protective role. There has been significant scientific interest in understanding how abdominal and gluteofemoral depots confer opposing metabolic risks. However, the study of regional adipose physiology in vivo remains challenging. We discuss some of the methodologies used. We focus specifically on the arteriovenous difference technique and present some insights into gluteofemoral adipose physiology.<br />Competing Interests: There are no conflicts of interest.<br /> (Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.)