Normal and cancer cells response on the thin films based on chitosan and tannic acid.

Authors :: Kaczmarek B
Miłek O
Nadolna K
Owczarek A
Kleszczyński K
Osyczka AM
Source :: Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2020 Feb; Vol. 62, pp. 104688. Date of Electronic Publication: 2019 Oct 21.
Publication Year :: 2020
Abstract: A novel aspect of tissue engineering is the material selective influence on the different cell types. The cell viability is a parameter which determine the cell ability to proliferate in the contact with material. In the experimental study the thin films based on chitosan and tannic acid mixture in ratio 80/20, 50/50 and 20/80 were tested. The surface roughness decreases with increasing tannic acid content. The cell culture was established on the proposed films. In vitro tests were carried out for the different cell lines as MNT-1, SK-MEL-28, Saos-2, HaCaT and BMSC. The result showed the dependence on the material influence on the various cell lines.<br /> (Copyright © 2019 Elsevier Ltd. All rights reserved.)

Subjects :: Biocompatible Materials
Cell Line
Cell Line, Tumor
Cell Survival drug effects
Chitosan chemistry
Humans
Surface Properties
Tannins chemistry
Tissue Engineering
Chitosan pharmacology
Tannins pharmacology

Language :: English
ISSN :: 1879-3177
Volume :: 62
Database :: MEDLINE
Journal :: Toxicology in vitro : an international journal published in association with BIBRA
Publication Type :: Academic Journal
Accession number :: 31648044
Full Text :: https://doi.org/10.1016/j.tiv.2019.104688

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