Pyrrole-quinazoline derivative as an easily accessible turn-off optical chemosensor for Cu 2+ and resultant Cu 2+ complex as a turn-on sensor for pyrophosphate in almost neat aqueous solution.

Authors :: Wang WW
Wang Y
Wu WN
Zhao XL
Xu ZQ
Xu ZH
Li XX
Fan YC
Source :: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2020 Feb 05; Vol. 226, pp. 117592. Date of Electronic Publication: 2019 Oct 14.
Publication Year :: 2020
Abstract: A simple chemosensor, 6-(1H-pyrrol-2-yl)-5,6-dihydro-benzo[4,5]imidazo[1,2-c]quinazoline (1), was synthesized via simple nucleophilic addition reaction coupled with Schiff base condensation. The probe 1 is aggregation-induced emission-active and could be used as an on-off fluorescence sensor toward Cu <superscript>2+</superscript> in H <subscript>2</subscript> O/CH <subscript>3</subscript> CN (99.5%, v/v) solution. Furthermore, the resultant Cu <superscript>2+</superscript> complex selectively responded to pyrophosphate (PPi) among various anions based on fluorescent on-off signal. In addition, the probe could be used for detecting Cu <superscript>2+</superscript> and PPi in HeLa cells.<br /> (Copyright © 2019 Elsevier B.V. All rights reserved.)

Language :: English
ISSN :: 1873-3557
Volume :: 226
Database :: MEDLINE
Journal :: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Publication Type :: Academic Journal
Accession number :: 31654904
Full Text :: https://doi.org/10.1016/j.saa.2019.117592

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