Back to Search
Start Over
Diagnostic yield of active case finding for tuberculosis at human immunodeficiency virus testing in Haiti.
- Source :
-
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease [Int J Tuberc Lung Dis] 2019 Nov 01; Vol. 23 (11), pp. 1217-1222. - Publication Year :
- 2019
-
Abstract
- SETTING: The Groupe Haïtien d'étude du Sarcome de Kaposi et des Infections Opportunistes (GHESKIO) Centres, Port-au-Prince, Haiti, facilitate "test and treat" strategies by screening all patients for tuberculosis (TB) at human immunodeficiency virus (HIV) testing. OBJECTIVE: 1) To determine the proportion of patients with chronic cough at HIV testing diagnosed with TB, stratified by HIV test results; and 2) to evaluate the additional diagnostic yield of Xpert <superscript>®</superscript> MTB/RIF vs. sputum microscopy. DESIGN: We conducted a retrospective cohort analysis including all adults tested for HIV at GHESKIO from August 2014 to July 2015. RESULTS: Of 29 233 adult patients tested for HIV, 2953 (10%) were diagnosed as HIV-positive. Chronic cough lasting ≥2 weeks was reported by 1116 (38%) HIV-positive patients; 984 (88%) were tested and 265 (27%) were diagnosed with TB. Chronic cough was reported by 5985 (23%) HIV-negative patients; 5654 (94%) were tested and 1179 (21%) were diagnosed with TB. Of all bacteriologically confirmed cases, 27% were smear-negative and Xpert-positive. Among all TB patients, 81% were HIV-negative. CONCLUSIONS: Screening for TB at HIV testing was high-yield, among both HIV-infected and HIV-negative individuals. Testing for both diseases should be conducted among patients who present with chronic cough at HIV testing.
- Subjects :
- Adult
Chronic Disease
Cough diagnosis
Cough etiology
Female
HIV Infections epidemiology
Haiti epidemiology
Humans
Male
Middle Aged
Mycobacterium tuberculosis isolation & purification
Retrospective Studies
Sputum microbiology
Tuberculosis epidemiology
Young Adult
HIV Infections diagnosis
Mass Screening methods
Tuberculosis diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1815-7920
- Volume :
- 23
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
- Publication Type :
- Academic Journal
- Accession number :
- 31718759
- Full Text :
- https://doi.org/10.5588/ijtld.18.0835