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Hypovitaminosis D in Hepatitis C patients and its relation with demographic and laboratory data.

Authors :
Jafar J
Junaid K
Saleem K
Amjed S
Arshad F
Amjed T
Raja N
Gillani A
Source :
JPMA. The Journal of the Pakistan Medical Association [J Pak Med Assoc] 2019 Nov; Vol. 69 (11), pp. 1637-1641.
Publication Year :
2019

Abstract

Objective: To determine the frequency of vitamin-D deficiency in hepatitis C patients and its relation with demographic and baseline laboratory data.<br />Methods: The cross-sectional study was conducted at the University Institute of Medical Laboratory Technology, Faculty of Allied Health Sciences, The University of Lahore, Pakistan, from April 3 to July 24, 2017, and comprised diagnosed hepatitis C genotype 3 patients aged 18-60 years. Demographic data was collected on a predesigned proforma. Tests included complete blood counts, liver function test, hepatitis C viral load and 25-hydroxy Vitamin-D level. Data was analysed using SPSS 24.<br />Results: Of the 115 patients, 54(47%) were male and 61(53%) were females. Mean vitamin-D level was 22.3±11.3. Total 25(21.7%) patients showed normal level of vitamin-D while the level was low in 90(78.3%) patients; 41(35.6%) showed vitamin-D insufficiency and 49(42.6%) vitamin-D deficiency. Significant effect of sun exposure was recorded on patient's vitamin-D level (p=0.00). Significantly low hepatitis C viral load was seen in patients with normal vitamin-D (p= 0. 02 6 ).<br />Conclusions: Patients with hepatitis C virus infection had high incidence of hypo-vitaminosis D.

Details

Language :
English
ISSN :
0030-9982
Volume :
69
Issue :
11
Database :
MEDLINE
Journal :
JPMA. The Journal of the Pakistan Medical Association
Publication Type :
Academic Journal
Accession number :
31740870
Full Text :
https://doi.org/10.5455/JPMA.301067.