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Alagille Syndrome and Chronic Arthritis: An International Case Series.

Authors :
Ferrara G
Giani T
Lieberman SM
Kremer C
Hong S
Indolfi G
Schulert G
Cron RQ
Mannion ML
Lapidus S
Armbrust W
Gonzales E
Jacquemin E
Koné-Paut I
Cimaz R
Source :
The Journal of pediatrics [J Pediatr] 2020 Mar; Vol. 218, pp. 228-230.e1. Date of Electronic Publication: 2019 Nov 17.
Publication Year :
2020

Abstract

We describe 10 children with Alagille syndrome and inflammatory arthritis. In our centers, the prevalence of chronic arthritis in patients with Alagille syndrome is approximately 50 times higher compared with the general population. Arthritis was refractory to most treatment. Patients with Alagille syndrome should routinely be screened for musculoskeletal symptoms.<br /> (Copyright © 2019 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1097-6833
Volume :
218
Database :
MEDLINE
Journal :
The Journal of pediatrics
Publication Type :
Academic Journal
Accession number :
31748120
Full Text :
https://doi.org/10.1016/j.jpeds.2019.10.042