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[Role of B-lymphocytes in inactivating allogenic stem cells].

Authors :
Man'ko VM
Khalat'ian NA
Rudneva TB
Source :
Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 1978 Nov (11), pp. 81-5.
Publication Year :
1978

Abstract

Antisera to membrane antigens of B lumphocytes eliminated the capacity of lymphocytes to inactivate allogenous stem cells by 60%; however, lymphocytes from the lymph nodes of B mice possessed no inactivating capacity. T-lymphocytes were the main criteria inactivating allogenous stem cells. Cooperating with T-lymphocytes, B-lymphocytes probably contributed to inactivation of precursor cells realized by T-lymphocytes. However, the presence of B-lymphocytes in the killer cells population was not a determinant, since T-lymphocytes were capable of inactivating allogenous stem cells without any participation of B-lymphocytes.

Details

Language :
Russian
ISSN :
0372-9311
Issue :
11
Database :
MEDLINE
Journal :
Zhurnal mikrobiologii, epidemiologii i immunobiologii
Publication Type :
Academic Journal
Accession number :
31752