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MYB20, MYB42, MYB43, and MYB85 Regulate Phenylalanine and Lignin Biosynthesis during Secondary Cell Wall Formation.
- Source :
-
Plant physiology [Plant Physiol] 2020 Mar; Vol. 182 (3), pp. 1272-1283. Date of Electronic Publication: 2019 Dec 23. - Publication Year :
- 2020
-
Abstract
- Lignin is a phenylpropanoid-derived polymer that functions as a major component of cell walls in plant vascular tissues. Biosynthesis of the aromatic amino acid Phe provides precursors for many secondary metabolites, including lignins and flavonoids. Here, we discovered that MYB transcription factors MYB20, MYB42, MYB43, and MYB85 are transcriptional regulators that directly activate lignin biosynthesis genes and Phe biosynthesis genes during secondary wall formation in Arabidopsis ( Arabidopsis thaliana ). Disruption of MYB20 , MYB42 , MYB43 , and MYB85 resulted in growth development defects and substantial reductions in lignin biosynthesis. In addition, our data showed that these MYB proteins directly activated transcriptional repressors that specifically inhibit flavonoid biosynthesis, which competes with lignin biosynthesis for Phe precursors. Together, our results provide important insights into the molecular framework for the lignin biosynthesis pathway.<br /> (© 2020 American Society of Plant Biologists. All Rights Reserved.)
- Subjects :
- Arabidopsis genetics
Arabidopsis Proteins genetics
Gene Expression Regulation, Plant
Plants, Genetically Modified genetics
Plants, Genetically Modified metabolism
Arabidopsis metabolism
Arabidopsis Proteins metabolism
Cell Wall metabolism
Lignin metabolism
Phenylalanine metabolism
Transcription Factors metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1532-2548
- Volume :
- 182
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Plant physiology
- Publication Type :
- Academic Journal
- Accession number :
- 31871072
- Full Text :
- https://doi.org/10.1104/pp.19.01070