Back to Search
Start Over
Photo-induced synthesis of molybdenum oxide quantum dots for surface-enhanced Raman scattering and photothermal therapy.
- Source :
-
Journal of materials chemistry. B [J Mater Chem B] 2020 Feb 07; Vol. 8 (5), pp. 1040-1048. Date of Electronic Publication: 2020 Jan 15. - Publication Year :
- 2020
-
Abstract
- By means of a simple and photo-induced method, four colors of molybdenum oxide quantum dots (MoO <subscript>x</subscript> QDs) have been synthesized, using Mo(CO) <subscript>6</subscript> as the structural guiding agent and molybdenum source. The as-prepared MoO <subscript>x</subscript> QDs display diverse optical properties due to the different configurations of oxygen vacancies in various nanostructures. Among them, crystalline molybdenum dioxide (MoO <subscript>2</subscript> ) with a deep blue color shows the most intense localized surface plasmon resonance effect in the near-infrared (NIR) region. The strong NIR absorption endows MoO <subscript>2</subscript> QDs with a high photothermal conversion efficiency of 66.3%, enabling broad prospects as a photo-responsive nanoagent for photothermal therapy of cancer. Moreover, MoO <subscript>2</subscript> QDs can also serve as a novel semiconductor substrate for ultrasensitive surface-enhanced Raman scattering (SERS) analysis of aromatic molecules, amino acids and antibiotics, with SERS performance comparable to that of noble metal-based substrates. The therapeutic applications of MoO <subscript>2</subscript> QDs open up a new avenue for tumor nanomedicine.
- Subjects :
- Apoptosis drug effects
Cell Survival drug effects
Hep G2 Cells
Humans
Materials Testing
Molybdenum chemistry
Nanostructures chemistry
Oxides chemical synthesis
Oxides chemistry
Particle Size
Photochemical Processes
Spectrum Analysis, Raman
Surface Properties
Temperature
Tumor Cells, Cultured
Molybdenum pharmacology
Oxides pharmacology
Photothermal Therapy
Quantum Dots chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 2050-7518
- Volume :
- 8
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Journal of materials chemistry. B
- Publication Type :
- Academic Journal
- Accession number :
- 31939980
- Full Text :
- https://doi.org/10.1039/c9tb02102g