A Queryable Graph Representation of Vascular Connectivity in the Whole Mouse Brain.

We construct a graph representation for the topology and geometry of the vasculature presenting across the whole mouse brain (dataset: Knife-Edge Scanning Microscope Brain Atlas India Ink). We use our graph representation to calculate preliminary estimates of the average radius as 4:8 μm, total vascular volume as 1:1000 mm ³ , total vascular surface area as 6:5511 cm ² , and total vascular length of 2866:6567 cm. We then isolate a posterior cerebral region, derive its graph representation, and then import that representation to a Neo4j graph database. We then detail how researchers can query this database online to isolate specific vascular networks for further analysis and reconstruction.