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Pharmacogenomics: An evolving clinical tool for precision medicine.

Authors :
Hockings JK
Pasternak AL
Erwin AL
Mason NT
Eng C
Hicks JK
Source :
Cleveland Clinic journal of medicine [Cleve Clin J Med] 2020 Feb; Vol. 87 (2), pp. 91-99.
Publication Year :
2020

Abstract

Pharmacogenomics, ie, the study of how an individual's genomic profile influences his or her response to drugs, has emerged as a clinical tool to optimize drug therapy. Certain variants in some genes increase the risk of severe, life-threatening adverse effects from certain drugs. Integrating pharmacogenomics into clinical practice to assist in drug selection and dosing has the potential to improve the outcomes of treatment, reduce the risk of drug-induced morbidity and death, and be cost-effective.<br /> (Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.)

Details

Language :
English
ISSN :
1939-2869
Volume :
87
Issue :
2
Database :
MEDLINE
Journal :
Cleveland Clinic journal of medicine
Publication Type :
Academic Journal
Accession number :
32015062
Full Text :
https://doi.org/10.3949/ccjm.87a.19073