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Pharmacogenomics: An evolving clinical tool for precision medicine.
- Source :
-
Cleveland Clinic journal of medicine [Cleve Clin J Med] 2020 Feb; Vol. 87 (2), pp. 91-99. - Publication Year :
- 2020
-
Abstract
- Pharmacogenomics, ie, the study of how an individual's genomic profile influences his or her response to drugs, has emerged as a clinical tool to optimize drug therapy. Certain variants in some genes increase the risk of severe, life-threatening adverse effects from certain drugs. Integrating pharmacogenomics into clinical practice to assist in drug selection and dosing has the potential to improve the outcomes of treatment, reduce the risk of drug-induced morbidity and death, and be cost-effective.<br /> (Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.)
- Subjects :
- Antidepressive Agents, Tricyclic adverse effects
Antidepressive Agents, Tricyclic metabolism
Clopidogrel metabolism
Codeine adverse effects
Cytochrome P-450 CYP2C19 genetics
Direct-To-Consumer Screening and Testing
Genetic Testing economics
Genotype
Humans
Selective Serotonin Reuptake Inhibitors adverse effects
Selective Serotonin Reuptake Inhibitors metabolism
Codeine metabolism
Cytochrome P-450 CYP2D6 genetics
Pharmacogenetics economics
Pharmacogenetics education
Pharmacogenetics organization & administration
Pharmacogenomic Variants
Precision Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 1939-2869
- Volume :
- 87
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Cleveland Clinic journal of medicine
- Publication Type :
- Academic Journal
- Accession number :
- 32015062
- Full Text :
- https://doi.org/10.3949/ccjm.87a.19073