Ethical issues related to brain organoid research.

Authors :: Hyun I
Scharf-Deering JC
Lunshof JE
Source :: Brain research [Brain Res] 2020 Apr 01; Vol. 1732, pp. 146653. Date of Electronic Publication: 2020 Feb 01.
Publication Year :: 2020
Abstract: This review provides a snapshot of the current ethical issues related to research with human brain organoids. The issues fall into the following main themes: research oversight; human biomaterials procurement and donor consent; translational delivery; animal research; and organoid consciousness and moral status. Each of these areas poses challenges for researchers, bioethicists, regulators, research institutions, and tissue banks. However, progress can be made if these parties build on past experiences with stem cell research, ethics, and policy, but adapted accordingly to new aspects of brain organoid research.<br /> (Copyright © 2020 Elsevier B.V. All rights reserved.)