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Protocol paper: Stepped wedge cluster randomized trial translating the ABCS into optimizing cardiovascular care for people living with HIV.
- Source :
-
Progress in cardiovascular diseases [Prog Cardiovasc Dis] 2020 Mar - Apr; Vol. 63 (2), pp. 125-133. Date of Electronic Publication: 2020 Feb 05. - Publication Year :
- 2020
-
Abstract
- People living with HIV (PWH) are at higher risk for cardiovascular disease (CVD) and stroke in comparison to their non-infected counterparts. The ABCS (aspirin-blood pressure control-cholesterol control-smoking cessation) reduce atherosclerotic (ASCVD) risk in the general population, but little is known regarding strategies for promoting the ABCS among PWH. Guided by the Consolidated Framework for Implementation Research (CFIR), we designed multilevel implementation strategies that target PWH and their clinicians to promote appropriate use of the ABCS based on a 10-year estimated ASCVD risk. Implementation strategies include patient coaching, automated texting, peer phone support, academic detailing and audit and feedback for the patient's clinician. We are evaluating implementation through a stepped wedge cluster randomized trial based on the Reach-Effectiveness-Adoption-Maintenance/Qualitative-Evaluation-for-Systematic-Translation (RE-AIM/QuEST) mixed methods framework that integrates quantitative and qualitative assessments. The primary outcome is change in ASCVD risk. Findings will have important implications regarding strategies for reducing ASCVD risk among PWH.<br /> (Copyright © 2020. Published by Elsevier Inc.)
- Subjects :
- Adult
Aged
Anti-HIV Agents adverse effects
Antihypertensive Agents therapeutic use
Cardiovascular Diseases diagnosis
Cardiovascular Diseases epidemiology
Female
HIV Infections diagnosis
HIV Infections epidemiology
Health Status
Humans
Hypoglycemic Agents therapeutic use
Male
Middle Aged
Multicenter Studies as Topic
Platelet Aggregation Inhibitors therapeutic use
Protective Factors
Randomized Controlled Trials as Topic
Risk Assessment
Risk Factors
Smoking Cessation
Time Factors
Treatment Outcome
United States
Viral Load
Anti-HIV Agents therapeutic use
Cardiovascular Diseases prevention & control
HIV Infections drug therapy
HIV Long-Term Survivors
Primary Prevention
Subjects
Details
- Language :
- English
- ISSN :
- 1873-1740
- Volume :
- 63
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Progress in cardiovascular diseases
- Publication Type :
- Academic Journal
- Accession number :
- 32035124
- Full Text :
- https://doi.org/10.1016/j.pcad.2020.02.003