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[Three cases of severe and fulminating ulcerative colitis with megacolon treated with continuous intravenous infusion of cyclosporine].

Authors :
Okano S
Sako M
Yoshimura N
Takazoe M
Source :
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology [Nihon Shokakibyo Gakkai Zasshi] 2020; Vol. 117 (2), pp. 157-164.
Publication Year :
2020

Abstract

Dilatation of the colon in severe and fulminating ulcerative colitis is a sign of toxic megacolon and emergency surgery is usually the favored treatment option. Here we describe our experience with three cases of ulcerative colitis with megacolon in which surgery was avoided by treating the patients with a continuous intravenous infusion of cyclosporine, with full cooperation of the surgeons. We recommend that continuous intravenous infusion of cyclosporine be considered as an effective option for the conservative management of severe, fulminating ulcerative colitis with megacolon.

Details

Language :
Japanese
ISSN :
0446-6586
Volume :
117
Issue :
2
Database :
MEDLINE
Journal :
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
Publication Type :
Academic Journal
Accession number :
32037361
Full Text :
https://doi.org/10.11405/nisshoshi.117.157