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Racial and ethnic disparities in the overall survival of women with epithelial ovarian cancer in Florida, 2001-2015.
- Source :
-
Cancer causes & control : CCC [Cancer Causes Control] 2020 Apr; Vol. 31 (4), pp. 333-340. Date of Electronic Publication: 2020 Feb 13. - Publication Year :
- 2020
-
Abstract
- Many studies have focused on white and black disparities in epithelial ovarian cancer (EOC) but fewer include Hispanics. Florida presents a unique opportunity to study racial/ethnic disparities. This study examined racial/ethnic disparities in the overall survival of women with EOC in Florida by histology. All EOC cases from 2001 through 2015 were identified in the Florida Cancer Database System (FCDS). Survival curves by race/ethnicity and histology were generated by Kaplan-Meier methods. Cox regression evaluated the associations between race/ethnicity, histology, and survival. Eligible EOC cases (nā=ā21,721) identified in the 2001-2015 FCDS were included in the study. The median survival for non-Hispanic whites (NHWs), non-Hispanic blacks (NHBs), and Hispanics was 31, 21, and 35 months, respectively (pā<ā0.001). NHB had an increased [AHR 1.23 (95% CI 1.15, 1.30)] and Hispanics a nonsignificant decreased hazard [AHR 0.96 (95% CI 0.91, 1.02)] of death compared to NHW after controlling for other demographic, treatment, and tumor characteristics. Relative to NHWs, NBH had worse survival while Hispanics had equivalent survival. Future research should consider evaluating genetic and epigenetic modifications, and prevalence of cancer syndromes to further elucidate the etiologies of disease in these disparate populations.
- Subjects :
- Black or African American statistics & numerical data
Aged
Ethnicity statistics & numerical data
Female
Florida epidemiology
Health Status Disparities
Hispanic or Latino statistics & numerical data
Humans
Middle Aged
Prevalence
Registries
White People statistics & numerical data
Carcinoma, Ovarian Epithelial ethnology
Carcinoma, Ovarian Epithelial mortality
Ovarian Neoplasms ethnology
Ovarian Neoplasms mortality
Subjects
Details
- Language :
- English
- ISSN :
- 1573-7225
- Volume :
- 31
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Cancer causes & control : CCC
- Publication Type :
- Academic Journal
- Accession number :
- 32052218
- Full Text :
- https://doi.org/10.1007/s10552-020-01276-2